Week 16 NFL Odds: Early Lines for Every Game


The NFL regular season is winding down and Week 16 brings with it some intriguing matchups. With the playoffs right around the corner, teams are pushing hard to secure their spot in the postseason. This week’s slate of games offers some mouthwatering matchups that could go a long way in deciding which teams make the playoffs. Before you make any bets, be sure to check out the NFL odds for every game in Week 16 of the NFL season.

  • Jacksonville Jaguars at New York Jets

The Jacksonville Jaguars and New York Jets meet in a Week 16 matchup that could be a good indicator of which teams will reach the playoffs. The Jaguars are currently listed as 1.5 point favorites, with both teams having -110 co-favorites to win. In this game, the total scoring Over/Under is 38.5 points scored by both teams combined. This matchup features two teams that have had success this season, so this should be an exciting and competitive game. The Jaguars have the edge in terms of talent, but the Jets have been a surprise team this season and could pull off the upset if they play their cards right. Who will come out on top? Tune in to find out!

  • Buffalo Bills at Chicago Bears

The Bills are heavily favored to win this game, having an 8.5 point spread over the Bears and with a moneyline of -400. The total scoring Over/Under is set at 41.5 points combined by both teams. Despite the Bears’ homefield advantage, the Bills have been on a roll since the beginning of the season and appear ready to continue their winning streak. This is sure to be an exciting match-up and one worth watching!

  • Detroit Lions at Carolina Panthers

The Detroit Lions are favored to win by more than 2.5 points, making them -143 favorites on the moneyline. A bet of $10 would return $16.99. The Carolina Panthers are +110 underdogs to win, and a bet of $10 would return $21. The over/under for this game is 44.5 points, as both teams look to score a combined total of 45 or more.

  • New Orleans Saints at Cleveland Browns

This week, the Browns are favored to beat the Saints by three points, with a moneyline of -162. The total scoring Over/Under is 31.5 points, so the teams should combine for around that many points. The Saints have struggled this season, but still boast one of the most potent offenses in the league. Meanwhile, the Browns have been surprisingly consistent and now hold the record for most wins in a single season since their return to the NFL in 1999. It should be an intriguing matchup between two teams trending in opposite directions.

  • Houston Texans at Tennessee Titans

The Titans are favored to win at home by 7 points, with a moneyline of -333. The over/under total is set at 38.5 points combined. Both teams have had their fair share of success this season, with the Titans standing at 8-6 and the Texans at 4-10. The Texans are hoping Deshaun Watson can lead the team to an upset win, while the Titans will rely on Ryan Tannehill to get the job done. Whoever can make the key plays in this matchup will come out on top.